Oup Management Co 13F annual report

Oup Management Co is an investment fund managing more than $58.6 billion ran by Matthew Cohen. There are currently 12 companies in Mr. Cohen’s portfolio. The largest investments include Centessa Pharmaceuticals Plc and Dice Therapeutics Inc., together worth $30.7 billion.

$58.6 billion Assets Under Management (AUM)

As of 31st July 2023, Oup Management Co’s top holding is 2,937,615 shares of Centessa Pharmaceuticals Plc currently worth over $18.2 billion and making up 31.0% of the portfolio value. In addition, the fund holds 268,346 shares of Dice Therapeutics Inc. worth $12.5 billion. The third-largest holding is Aerovate Therapeutics Inc. worth $10.4 billion and the next is Cyteir Therapeutics, Inc. worth $6.39 billion, with 2,459,572 shares owned.

Currently, Oup Management Co's portfolio is worth at least $58.6 billion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at Oup Management Co

The Oup Management Co office and employees reside in Bala Cynwyd, Pennsylvania. According to the last 13-F report filed with the SEC, Matthew Cohen serves as the Managing Member at Oup Management Co.

Recent trades



There are companies that Oup Management Co is getting rid of from its portfolio. Oup Management Co closed its position in Ionq, Inc. on 7th August 2023. It sold the previously owned 389,668 shares for $2.4 billion.

One of the smallest hedge funds

The two most similar investment funds to Oup Management Co are Surience Private Wealth and Rob Exploration. They manage $58.9 billion and $58.9 billion respectively.


Matthew Cohen investment strategy

Oup Management Co’s portfolio is diversified across 2 sectors. Currently, their heaviest sector is Health Care — making up 13.9% of the total portfolio value. The fund focuses on investments in the United States as 41.7% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are small-cap stocks. Stocks with a size of more than $100 million in market cap make up 17% of the total holdings value. On the other hand, large-cap stocks make up only approximately 0.1% of the portfolio. The average market cap of the portfolio companies is close to $180 million.

The complete list of Oup Management Co trades based on 13F SEC filings

These positions were updated on August 7th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
Centessa Pharmaceuticals Plc
No change
2,937,615
$18,183,837,000 31.01%
Dice Therapeutics Inc.
No change
268,346
$12,467,355,000 21.26%
Aerovate Therapeutics Inc.
No change
603,762
$10,354,518,000 17.66%
Cyteir Therapeutics, Inc.
No change
2,459,572
$6,394,887,000 10.91%
Pmv Pharmaceuticals Inc
No change
989,232
$6,192,592,000 10.56%
Ionq, Inc.
Closed
389,668
$2,396,458,000
Prime Medicine, Inc.
Closed
121,255
$1,491,437,000
Vor Biopharma Inc.
No change
374,714
$1,157,866,000 1.97%
Graphite Bio
No change
406,308
$1,056,401,000 1.80%
Selecta Biosciences Inc
No change
862,543
$966,048,000 1.65%
Effector Therapeutics, Inc.
No change
1,025,697
$851,534,000 1.45%
Precision BioSciences, Inc.
No change
1,123,913
$591,178,000 1.01%
Spero Therapeutics Inc
No change
249,070
$361,152,000 0.62%
Homology Medicines Inc
No change
64,000
$56,640,000 0.10%
No transactions found
Showing first 500 out of 14 holdings